PI biography

Joe McPhee is an Assistant Professor in the Department of Chemistry and Biology at Ryerson University where his research group studies virulence factors associated with adherent-invasive Escherichia coli (AIEC), a bacterial pathobiont that is strongly associated with Crohn’s disease.


He received a Bachelor of Science (Hons.) in Chemistry and Biology from St. Francis Xavier University in Antigonish, Nova Scotia. He received his PhD from the Department of Microbiology and Immunology at the University of British Columbia for work done in the laboratory of Dr. Bob Hancock, one of the world’s foremost experts in the development of, and resistance to, cationic antimicrobial peptides. While there, he received extensive training in molecular biology, bacterial gene regulation and microbiology. He undertook post-doctoral research in Dr. Jim Bliska’s lab at Stony Brook University where he studied virulence factors of the enteropathogen Yersinia pseudotuberculosis and the causative agent of plague, Y. pestis utilizing small animal models of host-pathogen interactions. He returned to Canada in 2011 to research adherent-invasiveEscherichia coli in the laboratory of Brian Coombes at McMaster University. While there, he was a member of a team of researchers responsible for developing an animal model for this pathogen as well as characterizing genes associated with bacterial fitness.