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Cho YH, Fadle Aziz MR, Malpass A, Sutradhar T, Bashal J, Cojocari V, McPhee JB. Omptin Proteases of Enterobacterales Show Conserved Regulation by the PhoPQ Two-Component System but Exhibit Divergent Protection from Antimicrobial Host Peptides and Complement. Infection and Immunity. 2022 Dec 19. doi: https://doi.org/10.1128/iai.00518-22

Cho YH, Renouf MJ, Omotoso O, McPhee JB. Inflammatory bowel disease-associated adherent-invasive Escherichia coli have elevated host-defense peptide resistance. FEMS Microbiol Lett. 2022 Oct 8:fnac098. doi: 10.1093/femsle/fnac098. Online ahead of print. PMID: 36208952

Lau TC, Fiebig-Comyn AA, Shaler CR, McPhee JB, Coombes BK, Schertzer JD. Low dietary fiber promotes enteric expansion of a Crohn’s disease-associated pathobiont independent of obesity. Am J Physiol Endocrinol Metab. 2021 Sep 1;321(3):E338-E350. doi: 10.1152/ajpendo.00134.2021. Epub 2021 Jul 19.

Kunwar CB, Birstonas S, McPhee JB, Barnett Foster D. Molecular basis of bile-salt- and iron-induced enterohaemorrhagic E. coli resistance to cationic antimicrobial peptides. Microbiology (Reading). 2020 Dec;166(12):1149-1159. doi: 10.1099/mic.0.000988. PMID: 33205745

Renouf MJ, Cho YH, McPhee JB. Emergent Behavior of IBD-Associated Escherichia coli During Disease. Inflamm Bowel Dis. 2019 Jan 1;25(1):33-44. doi: 10.1093/ibd/izy312. PMID: 30321333

Small CL, Xing L, McPhee JB, Law HT, Coombes BK. Acute infection gastroenteritis potentiates a Crohn’s disease pathobiont to fuel ongoing inflammation in the post-infectious period. PLOS Path. 2016 12(10) e1005907 Pubmed PMID 27711220.

Fukuto HS, Vadyvaloo V, McPhee JB, Poinar HN, Holmes EC, Bliska JB. A Single Amino Acid Change in the Response Regulator PhoP, Acquired during Yersinia pestis Evolution, Affects PhoP Target Gene Transcription and Polymyxin B Susceptibility. J Bacteriol. 2018 Apr 9;200(9):e00050-18. doi: 10.1128/JB.00050-18. Print 2018 May 1. PMID: 29440252

McPhee JB and Schertzer JD. Immunometabolism of obesity and diabetes: microbiota link compartmentalized immunity in the gut to metabolic tissue inflammation. Clin Sci (Lond) 2015 Dec 1;129(12):1083-96 doi: 10.1042/CS20150431 Pubmed PMID 26464517

McPhee JB, Small CL, Reid-Yu SA, Brannon JR, Le Moual H, Coombes BK. Host defense peptide resistance contributes to colonization and maximal intestinal pathology by Crohn’s disease-associated adherent-invasive Escherichia coli. Infect Immun. 2014 Aug;82(8):3383-93. doi: 10.1128/IAI.01888-14. Epub 2014 May 27. PubMed PMID: 24866805

Small CL, Reid-Yu SA, McPhee JB, Coombes BK. Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis. Nat Commun. 2013;4:1957. doi: 10.1038/ncomms2957. PubMed PMID: 23748852

McPhee JB, Mena P, Zhang Y, Bliska JB. Interleukin-10 induction is an important virulence function of the Yersinia pseudotuberculosis type III effector YopM. Infect Immun. 2012 Jul;80(7):2519-27. doi: 10.1128/IAI.06364-11. Epub 2012 Apr 30. PubMed PMID: 22547545

Bos KI, Schuenemann VJ, Golding GB, Burbano HA, Waglechner N, Coombes BK, McPhee JB, DeWitte SN, Meyer M, Schmedes S, Wood J, Earn DJ, Herring DA, Bauer P, Poinar HN, Krause J. A draft genome of Yersinia pestis from victims of the Black Death. Nature. 2011 Oct 12;478(7370):506-10. doi: 10.1038/nature10549. Erratum in: Nature. 2011 Dec 8;480(7376):278. PubMed PMID: 21993626

Fernández L, Gooderham WJ, Bains M, McPhee JB, Wiegand I, Hancock RE. Adaptive resistance to the “last hope” antibiotics polymyxin B and colistin in Pseudomonas aeruginosa is mediated by the novel two-component regulatory system ParR-ParS. Antimicrob Agents Chemother. 2010 Aug;54(8):3372-82. doi: 10.1128/AAC.00242-10. Epub 2010 Jun 14. PubMed PMID: 20547815

McPhee JB, Mena P, Bliska JB. Delineation of regions of the Yersinia YopM protein required for interaction with the RSK1 and PRK2 host kinases and their requirement for interleukin-10 production and virulence. Infect Immun. 2010 Aug;78(8):3529-39. doi: 10.1128/IAI.00269-10. Epub 2010 Jun 1. PubMed PMID: 20515922

McPhee JB, Tamber S, Bains M, Maier E, Gellatly S, Lo A, Benz R, Hancock RE. The major outer membrane protein OprG of Pseudomonas aeruginosa contributes to cytotoxicity and forms an anaerobically regulated, cation-selective channel. FEMS Microbiol Lett. 2009 Jun;296(2):241-7. doi: 10.1111/j.1574-6968.2009.01651.x. Epub 2009 May 14. PubMed PMID: 19486157.

Gooderham WJ, Gellatly SL, Sanschagrin F, McPhee JB, Bains M, Cosseau C, Levesque RC, Hancock RE. The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa. Microbiology. 2009 Mar;155(Pt 3):699-711. doi: 10.1099/mic.0.024554-0. PubMed PMID: 19246741.

McPhee JB, Bains M, Winsor G, Lewenza S, Kwasnicka A, Brazas MD, Brinkman FS, Hancock RE. Contribution of the PhoP-PhoQ and PmrA-PmrB two-component regulatory systems to Mg2+-induced gene regulation in Pseudomonas aeruginosa. J Bacteriol. 2006 Jun;188(11):3995-4006. PubMed PMID: 16707691

McPhee JB, Hancock RE. Function and therapeutic potential of host defence peptides. J Pept Sci. 2005 Nov;11(11):677-87. Review. PubMed PMID: 16103989.

Hancock RE, McPhee JB. Salmonella‘s sensor for host defense molecules. Cell. 2005 Aug 12;122(3):320-2. Review. PubMed PMID: 16096052.

McPhee JB, Scott MG, Hancock RE. Design of host defence peptides for antimicrobial and immunity enhancing activities. Comb Chem High Throughput
Screen. 2005 May;8(3):257-72. Review. PubMed PMID: 15892627.

Lewenza S, Falsafi RK, Winsor G, Gooderham WJ, McPhee JB, Brinkman FS, Hancock RE. Construction of a mini-Tn5-luxCDABE mutant library in Pseudomonas aeruginosa PAO1: a tool for identifying differentially regulated genes. Genome Res. 2005 Apr;15(4):583-9. PubMed PMID: 15805499

McPhee JB, Lewenza S, Hancock RE. Cationic antimicrobial peptides activate a two-component regulatory system, PmrA-PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa. Mol Microbiol. 2003 Oct;50(1):205-17. PubMed PMID: 14507375.